RESUMO
【Objective】 To analyze the risk factors of anemia in premature infants and the status of blood transfusion. 【Methods】 Clinical data of preterm infants with age ≤48 hours and hospitalization time ≥7 days, admitted to our hospital from August 2018 to July 2019, were collected. According to the Hb value, they were divided into the anemia group and the non-anemia group. The general information, disease occurrence, and treatment measures during hospitalization of the two groups were compared, and the risk factors affecting anemia were analyzed. 【Results】 A total of 169 cases were included in this study, including 88 cases in the anemia group and 81 cases in the non-anemia group. There were statistically significant differences between two groups in assisted reproduction 47(53.409) vs 33(40.741), basic Hb value 180.395(176.282, 184.508) vs 162.841(158.596, 167.085), maternal pregnancy anemia 27(30.682) vs 12(14.815), late-onset sepsis(LOS) 64(72.727) vs 31(38.272), mechanical ventilation 46(52.273) vs 10(12.346), neonatal respiratory distress syndrome(NRDS) 51(57.955) vs 26(32.099), coagulation dysfunction 27(30.682) vs 11(13.580) and average hospitalization days 31.276(26.885, 35.666) vs 15.798(14.251, 17.344), all P<0.05. Multivariate logistic results showed assisted reproduction, maternal pregnancy anemia, mechanical ventilation, coagulation dysfunction and average hospitalization days ≥20 were risk factors for preterm anemia. A total of 40 cases(23.669%) needed RBC transfusion to correct anemia during hospitalization, including 21 cases of very low birth weight infants(VLBWI). 8 patients(38.095%) received RBC transfusion ≥3 times during VLBWI hospitalization. The incidence of bronchopulmonary dysplasia(BPD) in the multiple transfusion group(≥3 times of RBC transfusion) was higher than in the non-multiple transfusion group. 【Conclusion】 Maternal anemia during pregnancy, assisted reproduction, mechanical ventilation, coagulation dysfunction and average hospitalization days are the related factors affecting the occurrence of anemia. The occurrence of BPD may be associated with multiple blood transfusions, but there is no clear evidence to prove that blood transfusion is an independent risk factor for the development of BPD, and a large sample, multi-center study is needed.
RESUMO
Objective@#To understand the association between childhood abuse experience and health risk behaviors among college students, providing references for childhood abuse and health risk behavior prevention.@*Methods@#During Mar. to Apr. of 2016, 918 college students from 2 universities in Nanchong city were selected through cluster sampling, the survey included general demographic characteristics, childhood abuse experiences and health risk behaviors. Chi square test was used for univariate analysis, and Logistic regression was used for multivariate analysis.@*Results@#A total of 720(78.43%) of participants reported at least one type of health risk behaviors, overeating was the most common type[595(64.81%)]. The number of adolescent reporting smoking, drinking 5 or more beers at a time, fighting and suicidal ideation was 146(15.90%), 271(29.52%), 224(24.40%), 205( 22.33 %), respectively. Multivariate Logistic regression analysis showed that a significant positive association between experiencing at least one kind of childhood abuse and the behaviors of fighting, suicidal ideation, and overeating; between childhood emotional neglect with smoking and suicidal ideation; between childhood emotional abuse with fighting, suicidal ideation, and overeating; and between childhood sexual abuse with smoking( P <0.05).@*Conclusion@#Health risk behavior in college students is popular. Childhood abuse can increase the risk of health risk behaviors of college students.
RESUMO
Objective:To explore the clinical application value of MRI in quantitative evaluation of anterior cruciate ligament mucoid degeneration (ACL-MD).Methods:From March to July 2020, 40 patients who were scheduled to undergo arthroscopic treatment were prospectively collected in the First Affiliated Hospital of Kunming Medical University.The anterior cruciate ligament tissue from the lateral edge of the tibial end was taken during the operation. Based on the pathologicalre sults, the patients were divided into the ACL-MD group ( n=19) and the normal group ( n=21). The sagittal plane three-dimensional steady-state rapid precession (3D-FIESTA), T 1 mapping, T 2 mapping, and T 2* mapping were performed before the knee joint surgery, and the scanned images were post-processed and analyzed to measure the T 1, T 2, and T 2* values of the tibial end of the anterior cruciate ligament.The relaxation time of the ACL-MD group and the normal group was compared using independent sample t test. The ROC curve was drawn using each parameter and the areas under the curve (AUC) for the diagnosis of ACL-MD were obtained.DeLong test was used to compare the differences of AUCs. Results:The T 1 [(1 291.9±273.4) ms], T 2 [(54.8±10.6) ms], and T 2* values [(30.6±6.4) ms] of anterior cruciate ligaments in the ACL-MD group were significantly higher than those in the normal group [ (1 087.0±121.0), (44.8±7.1), (20.4±4.8) ms; t=3.011, 3.473, 5.658, all P<0.001]. The AUCs of T 1, T 2, T 2* were 0.747, 0.764, 0.912, sensitivity of 63.2%, 63.2%, 100%, and the specificity of 100%, 95.2%, 76.2% in diagnosing ACL-MD. The AUC of the T 2* value was higher than those of the T 1 and T 2 values, and the differences were statistically significant ( Z=1.734, 2.162, P=0.043, 0.031). Conclusion:T 1, T 2, T 2*values measured by MRI quantitative imaging have high performance in assessing knee joint ACL-MD, and T 2* value has the largest AUC and the highest diagnostic efficiency.
RESUMO
Objective To investigate the diagnostic value of the acoustic radiation force impulse (ARFI) imaging technology and AST/PLT ratio index (APRI) for the assessment of the liver fibrosis in non-alcoholic fatty liver disease (NAFLD) patients.Method One hundred and thirty-six patients with NAFLD were included from May 2012 to May 2015 in the Third People's Hospital of Shenzhen.The subjects underwent liver biopsy,liver function and blood count test,as well as real-time ultrasonic elastography examination.The measurements of real-time ultrasonic elastography by ARFI technology used an ultrasonic instrument ACUSON S2000.The APRI was calculated according to the following formula,APRI=AST/PLT.ARFI and APRI were compared by correlation with liver fibrosis stage in NAFLD.Referring to the histologic fibrosis stage on liver biopsy,all the ARFI and the APRI value were assessed by using receiver operating characteristic (ROC) curve analysis.The corresponding cut-off values,sensitivity and specificity were also calculated and compared.One hundred and thirty-six patients with non alcoholic fatty liver disease were included in this study.Both of ARFI and APRI index were measured and calculated,and the results were compared with the pathological examination as gold standard.Results All patients underwent ARFI test.Compared with the patients with S0 and S 1,the ARFI of S4 were decreased significantly and the difference was statistically significant (both P ＜ 0.05).There was no significant difference in APRI index (P ＞ 0.05) among different stages of fibrosis.ROC curve of different diagnosis methods were drawn..The area under the ROC curve of diagnosing S2,S3 and S4 or higher stages nonalcoholic fatty liver disease by ARFI were 0.714,0.765,0.853,and corresponding value of APRI were 0.653,0.577 and 0.611.Compared with the APRI index,the area under the ROC curve of the ARFI technique in evaluating the degree of liver fibrosis in non alcoholic fatty liver disease was increased significantly,and the area under the curve of S4 was the highest.The cut-offARFI index of diagnosing severe hepatic fibrosis was 1.362 m/s.Conclusions As a non-invasive technology,ARFI is more accurate in evaluating liver fibrosis in patients with NAFLD than APRI.ARFI technology has potential value for quantitative evaluation of the liver fibrosis for NAFLD.
RESUMO
Objective To study the volume of lateral cerebral ventricle in neonates with threedimensional ultrasonography(3F-US),and to investigate the influence of sex,body weight(BW),head circumference(HC)and gestational age(GA) on it. Methods A total of 255 healthy neonates (GA 28~40 weeks) were examined with 3D cranial ultrasound. The ultrasonography was performed with anterior fontanel as the acoustic window,and the data were aquired at the deck of third ventricle on coronal section.The 3D image on the screen was constructed automatically and the volume of lateral cerebral ventricle was (P=0.809),and there was negative correlation between the volume of lateral cerebral ventricle and GA(r=-0.971). The correlation between the volume of lateral cerebral ventricle and HC was positive(r≥According to the relationships among HC(X 1),GA(X 2)and volume of lateral cerebral ventricle(Y),a linear regression equation Y=2.298-0.011 X1-0.04 X2 was obtained(the determinate coefficient R2 was accurately,which would be helpful to the evaluation on the cerebral maturity and the diagnosis of cerebral desease in neonates without wound.